Hexapropymate
Hexapropymate is a sedative and hypnotic medication in the pyrithyldione group of drugs. It is used in the treatment of insomnia and other sleep disorders. Hexapropymate is also used as a premedication before surgery to induce sedation and reduce anxiety.
Pharmacology
Hexapropymate acts by enhancing the action of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter, which means it reduces the activity of the neurons to which it binds. By enhancing the action of GABA, hexapropymate helps to calm the brain and induce sleep.
Side effects
Common side effects of hexapropymate include drowsiness, dizziness, and confusion. Less common side effects can include memory problems, depression, and hallucinations. In rare cases, hexapropymate can cause severe allergic reactions, including anaphylaxis.
Contraindications
Hexapropymate is contraindicated in patients with known hypersensitivity to the drug or any of its components. It is also contraindicated in patients with severe liver disease, acute narrow-angle glaucoma, and in patients who are pregnant or breastfeeding.
Interactions
Hexapropymate can interact with other medications, including other sedatives, hypnotics, and alcohol. These interactions can increase the sedative effects of hexapropymate and increase the risk of side effects.
See also
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