Flutazolam

Flutazolam is a benzodiazepine derivative drug which is a type of psychoactive drug. It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties. Flutazolam was patented in 1966 and its medical use began in 1974. It is not approved for use in the United States or Europe, but is available in Japan and some other countries.

Pharmacology

Flutazolam is a benzodiazepine which means it acts on the GABA receptor to produce its medical and adverse effects. It has a medium to long duration of action and is used in the treatment of anxiety disorders, insomnia, and for the management of acute alcohol withdrawal syndrome.

Medical Uses

Flutazolam is primarily used for the treatment of anxiety disorders and insomnia. It is also used in the management of acute alcohol withdrawal syndrome. It has been found to be more effective in the treatment of anxiety disorders than other benzodiazepines due to its longer duration of action.

Side Effects

The most common side effects of flutazolam are drowsiness, dizziness, and loss of coordination. Other side effects can include confusion, depression, and memory impairment. Long-term use of flutazolam can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.

Interactions

Flutazolam can interact with other medications, including other CNS depressants, alcohol, and certain antidepressants. These interactions can increase the risk of side effects and can potentially be dangerous.

See Also

• Benzodiazepine
• GABA receptor
• Anxiety disorders
• Insomnia

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  Flutazolam chemical structure

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  Flutazolam ball-and-stick model