Tetrazepam
Tetrazepam
Tetrazepam (pronounced: te-tra-ze-pam) is a benzodiazepine derivative with anxiolytic, anticonvulsant, muscle relaxant and slightly hypnotic properties. It was discovered by Hoffmann-La Roche in 1963 and is indicated for the treatment of anxiety, insomnia, and for the control of muscle spasms.
Etymology
The term "Tetrazepam" is derived from the systematic (IUPAC) name 7-chloro-5-(cyclohexen-1-yl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one. The prefix "tetra-" refers to the presence of four nitrogen atoms in the benzodiazepine ring structure, while "-zepam" is a common suffix for benzodiazepine drugs.
Pharmacology
Tetrazepam, like other benzodiazepines, works by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, resulting in sedative, sleep-inducing, anxiolytic, anticonvulsant, and muscle relaxant properties.
Side Effects
Common side effects of Tetrazepam include drowsiness, fatigue, muscle weakness, and ataxia. Less common side effects can include confusion, depression, and changes in libido. Long-term use of Tetrazepam can lead to tolerance, dependence, and withdrawal syndrome upon discontinuation.
Related Terms
- Benzodiazepine
- Anxiolytic
- Anticonvulsant
- Muscle relaxant
- Hypnotic
- Gamma-aminobutyric acid
- Tolerance
- Dependence
- Withdrawal syndrome
External links
- Medical encyclopedia article on Tetrazepam
- Wikipedia's article - Tetrazepam
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