Valofane

From WikiMD's medical encyclopedia


Overview

Valofane is a synthetic compound used in the treatment of various medical conditions. It is primarily known for its role in anesthesia and pain management. Valofane is classified as a pharmaceutical drug and is administered under strict medical supervision.

Chemical Properties

Valofane is a complex chemical compound with a unique molecular structure that allows it to interact effectively with the central nervous system. Its chemical formula is C12H15NO3, and it is known for its high solubility in both water and lipids, which facilitates its rapid absorption and distribution in the body.

Mechanism of Action

Valofane works by modulating the activity of neurotransmitters in the brain. It primarily acts on the GABA receptors, enhancing the inhibitory effects of the neurotransmitter gamma-aminobutyric acid. This action results in a calming effect on the nervous system, making it effective for inducing sedation and analgesia.

Clinical Uses

Valofane is used in various clinical settings, including:

  • Anesthesia: As an adjunct in general anesthesia, Valofane helps in maintaining a stable anesthetic state during surgical procedures.
  • Pain Management: It is used in the management of chronic pain conditions, providing relief by altering pain perception.
  • Sedation: In intensive care units, Valofane is used to sedate patients who require mechanical ventilation.

Administration and Dosage

Valofane is administered intravenously, and the dosage is carefully calculated based on the patient's weight, age, and medical condition. It is crucial to monitor the patient closely to avoid potential side effects and complications.

Side Effects

Common side effects of Valofane include:

Severe side effects may include allergic reactions, hypotension, and bradycardia.

Contraindications

Valofane is contraindicated in patients with a known hypersensitivity to the drug or its components. It should be used with caution in patients with liver disease, kidney disease, or respiratory disorders.

Related Pages

Gallery

Chemical structure of Valofane
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Contributors: Prab R. Tumpati, MD