Pregnanolone

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Pregnanolone

Pregnanolone, also known as 3α-hydroxy-5β-pregnan-20-one, is a neurosteroid that is produced in the adrenal glands and the brain. It is a metabolite of progesterone and can act as a potent positive allosteric modulator at the GABA_A receptor.

Pronunciation

Pregnanolone is pronounced as preɡˈnanəˌlōn.

Etymology

The term "Pregnanolone" is derived from "Pregnane", a parent hydrocarbon for two series of steroids stemming from 5α-pregnane and 5β-pregnane, and "olone" indicating a ketone group.

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