Methylmethaqualone
Overview of the drug Methylmethaqualone
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Methylmethaqualone is a quinazolinone-class sedative and hypnotic drug that is structurally related to methaqualone. It was developed in the 1960s and has similar effects to methaqualone, including sedation, anxiolysis, and muscle relaxation.
Chemical structure and properties
Methylmethaqualone is a derivative of methaqualone, with a methyl group added to the nitrogen atom of the quinazolinone ring. This modification alters its pharmacokinetic properties, potentially affecting its potency and duration of action.
Pharmacology
Methylmethaqualone acts as a central nervous system depressant. It is believed to exert its effects by modulating GABA receptors, similar to other sedative-hypnotic drugs. This action results in increased inhibitory neurotransmission, leading to the drug's calming effects.
Medical use
Methylmethaqualone was initially developed for use as a sedative and hypnotic agent. However, due to concerns about its potential for abuse and addiction, its medical use has been limited. It is not commonly prescribed today and is considered a controlled substance in many countries.
Side effects
The side effects of methylmethaqualone are similar to those of other sedative-hypnotics and may include drowsiness, dizziness, nausea, and headache. In higher doses, it can cause more severe effects such as respiratory depression, hypotension, and coma.
Legal status
Due to its potential for abuse and addiction, methylmethaqualone is classified as a controlled substance in many jurisdictions. Its legal status varies by country, but it is generally subject to strict regulation.
Related compounds
Methylmethaqualone is chemically related to several other quinazolinone derivatives, including:
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