Vigabatrin
Vigabatrin
Vigabatrin (pronounced: vi-ga-ba-trin), also known by its brand name Sabril, is an antiepileptic drug used in the treatment of epilepsy.
Etymology
The name "Vigabatrin" is derived from its chemical name: vinyl gamma-aminobutyric acid transaminase inhibitor'.
Usage
Vigabatrin is primarily used to treat complex partial seizures, a type of epilepsy. It is also used in the treatment of infantile spasms, a rare disorder that occurs in infants.
Mechanism of Action
Vigabatrin works by increasing the level of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. It does this by irreversibly inhibiting the enzyme GABA transaminase, which is responsible for breaking down GABA.
Side Effects
Common side effects of Vigabatrin include drowsiness, weight gain, and tremors. A more serious but less common side effect is a permanent loss of peripheral vision.
Related Terms
- Antiepileptic drugs
- Complex partial seizures
- Infantile spasms
- Gamma-aminobutyric acid
- GABA transaminase
External links
- Medical encyclopedia article on Vigabatrin
- Wikipedia's article - Vigabatrin
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