Carboxamide
Carboxamide
Carboxamide (pronunciation: kar-bok-sa-mide) is a functional group in organic chemistry that is derived from carboxylic acids. Its general formula is R-CO-NR'R, where R, R', and R can be a variety of carbon-containing substituents.
Etymology
The term "carboxamide" is derived from the words "carboxylic acid" and "amide". The "carboxy" part refers to the carboxyl group (-COOH) found in carboxylic acids, and the "amide" part refers to the amide group (-NH2), which replaces the hydroxyl group (-OH) in carboxylic acids to form carboxamides.
Structure and Properties
Carboxamides are characterized by the presence of a carbonyl group (C=O) and an amide group (N-H or N-R) attached to the same carbon atom. The carbonyl group is polar due to the electronegativity difference between the carbon and oxygen atoms, and the amide group can participate in hydrogen bonding, making carboxamides polar compounds.
Related Terms
- Carboxylic Acid: The parent compound of carboxamides, characterized by the presence of a carboxyl group (-COOH).
- Amide: A functional group characterized by a nitrogen atom connected to a carbonyl carbon atom.
- Functional Group: A specific group of atoms within a molecule that is responsible for the characteristic chemical reactions of that molecule.
- Organic Chemistry: The branch of chemistry that deals with the study of the structure, properties, composition, reactions, and synthesis of organic compounds.
Uses
Carboxamides have a wide range of uses in the chemical industry. They are used in the synthesis of various pharmaceuticals, dyes, and polymers. Some carboxamides, such as dimethylformamide (DMF) and dimethylacetamide (DMA), are used as solvents in chemical reactions.
External links
- Medical encyclopedia article on Carboxamide
- Wikipedia's article - Carboxamide
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