Pirlimycin
Pirlimycin is an antibiotic used in veterinary medicine to treat mastitis in dairy cattle. It is a member of the lincosamide class of antibiotics and works by inhibiting protein synthesis in susceptible bacteria.
Chemistry
Pirlimycin is a semi-synthetic antibiotic, derived from lincomycin. It is a white to off-white crystalline powder that is soluble in water. The chemical name for pirlimycin is N-[[2-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]ethyl]-6,11-dihydro-4-(1-methyl-3,3-diphenyl-propyl)-1H-pyrrolo[2,1-c][1,4]benzodiazepin-1-one.
Pharmacology
Pirlimycin is bacteriostatic, meaning it inhibits the growth of bacteria rather than killing them directly. It works by binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis. Pirlimycin is effective against a range of Gram-positive bacteria, including Staphylococcus aureus and Streptococcus agalactiae, which are common causes of bovine mastitis.
Usage
Pirlimycin is administered intramammary, meaning it is injected directly into the udder. It is used to treat mastitis in lactating dairy cows, and is particularly effective against infections caused by Staphylococcus aureus and Streptococcus agalactiae. Treatment typically involves a single dose, although severe infections may require additional doses.
Safety
As with all antibiotics, overuse of pirlimycin can lead to the development of antibiotic resistance. Therefore, it should be used only when necessary and under the supervision of a veterinarian. Milk from cows treated with pirlimycin should not be used for human consumption until a specified withdrawal period has passed to ensure that residues of the drug have been eliminated.
See also
| This article is a stub. You can help WikiMD by registering to expand it. |
This veterinary medicine related article is a stub. You can help WikiMD by expanding it.
Ad. Transform your life with W8MD's
GLP-1 weight loss injections special from $29.99 with insurance
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
