Apramycin
Apramycin
Apramycin (/əˈpræmɪsɪn/) is an aminoglycoside antibiotic that is used in veterinary medicine. It is derived from the bacterium Streptomyces tenebrarius and is effective against both Gram-positive and Gram-negative bacteria.
Etymology
The term "Apramycin" is derived from the Latin apra, meaning "open", and mycin, a common suffix for antibiotics derived from Streptomyces species. The name thus suggests the antibiotic's broad-spectrum activity.
Pharmacology
Apramycin works by binding to the bacterial ribosome, inhibiting protein synthesis and thereby stopping bacterial growth. It is particularly effective against Escherichia coli and other Enterobacteriaceae, and is often used to treat gastrointestinal infections in animals.
Related Terms
- Aminoglycoside: A class of antibiotics that includes apramycin. Aminoglycosides work by binding to bacterial ribosomes and inhibiting protein synthesis.
- Antibiotic: A type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections.
- Streptomyces tenebrarius: The bacterium from which apramycin is derived.
- Ribosome: A complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis.
- Escherichia coli: A type of bacteria that lives in your intestines. Most types of E. coli are harmless and even help keep your digestive tract healthy.
- Enterobacteriaceae: A large family of Gram-negative bacteria that includes, along with many harmless symbionts, many of the more familiar pathogens.
External links
- Medical encyclopedia article on Apramycin
- Wikipedia's article - Apramycin
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