Sulfalene

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Sulfalene

Sulfalene (pronounced sul-fa-leen) is a sulfonamide antimicrobial medication used primarily in the treatment of malaria. It is also known as sulfametopyrazine.

Etymology

The term "sulfalene" is derived from its chemical structure, which includes a sulfonamide group and a pyrazine ring. The "-lene" suffix is commonly used in chemical nomenclature to denote a particular type of ring structure.

Usage

Sulfalene is used in combination with pyrimethamine in a treatment regimen for malaria. This combination is known as Fansidar, which is a registered trademark of Roche. Sulfalene works by inhibiting the growth of the malaria parasite in the blood.

Related Terms

  • Sulfonamide: A group of synthetic antimicrobial agents that contain the sulfonamide group.
  • Pyrazine: A heterocyclic aromatic organic compound with the chemical formula C4H4N2.
  • Malaria: A mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans belonging to the Plasmodium type.
  • Pyrimethamine: A medication used with leucovorin to treat the parasitic diseases toxoplasmosis and cystoisosporiasis.
  • Fansidar: A combination of sulfadoxine and pyrimethamine, and is used to treat or prevent malaria.

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