Mecillinam

Mecillinam is an antibiotic that belongs to the penicillin family. It is primarily used to treat urinary tract infections (UTIs) caused by Gram-negative bacteria. Mecillinam is also known by the brand names Selexid and Pivmecillinam.

Etymology

The name "Mecillinam" is derived from the chemical structure of the drug, which includes a 6-methyl-2-phenyl substituent on the penam core structure.

Pharmacology

Mecillinam is a beta-lactam antibiotic, which means it works by inhibiting the synthesis of bacterial cell walls. It is particularly effective against Gram-negative bacteria, including Escherichia coli and Proteus mirabilis, which are common causes of UTIs.

Clinical Use

Mecillinam is primarily used to treat UTIs. It is often used when other antibiotics are ineffective or cannot be used due to resistance or allergies. Mecillinam can be taken orally or administered intravenously.

Side Effects

Like all antibiotics, Mecillinam can cause side effects. These may include nausea, vomiting, diarrhea, and rash. In rare cases, it can cause serious allergic reactions.

Related Terms

• Beta-lactam antibiotic
• Penicillin
• Urinary tract infection
• Gram-negative bacteria
• Escherichia coli
• Proteus mirabilis

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