Doripenem

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Doripenem

Doripenem (/dɔːrɪˈpɛnɛm/) is a carbapenem type antibiotic used in the treatment of various bacterial infections. It is marketed under the trade name Doribax by Janssen Pharmaceutica.

Etymology

The term "Doripenem" is derived from the chemical structure of the drug, which includes a doripenem side chain. The "-penem" suffix is common in the names of carbapenem antibiotics.

Pharmacology

Doripenem works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It is active against a wide range of Gram-positive and Gram-negative bacteria, including some strains resistant to other antibiotics.

Clinical Use

Doripenem is used to treat a variety of infections, including pneumonia, urinary tract infections, and intra-abdominal infections. It is also used in the treatment of sepsis and other serious infections.

Side Effects

Common side effects of Doripenem include nausea, diarrhea, and headache. More serious side effects may include allergic reactions, seizures, and Clostridium difficile-associated diarrhea.

See Also

References


External links

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