Fosfomycin
Fosfomycin
Fosfomycin (pronounced /fɒsfəˈmaɪsɪn/) is a broad-spectrum antibiotic that is primarily used for the treatment of urinary tract infections (UTIs). It is derived from the bacterium Streptomyces fradiae.
Etymology
The term "Fosfomycin" is derived from the chemical structure of the drug, which contains a phosphonic acid moiety (fosfo-) and a moiety derived from mycin (-mycin), a common ending for antibiotics.
Mechanism of Action
Fosfomycin works by inhibiting the enzyme MurA, which is involved in the first step of bacterial cell wall synthesis. This results in the death of the bacteria.
Usage
Fosfomycin is used to treat uncomplicated urinary tract infections caused by susceptible strains of Escherichia coli and Enterococcus faecalis. It is also used off-label for the treatment of certain types of multidrug-resistant bacterial infections.
Side Effects
Common side effects of fosfomycin include nausea, diarrhea, and headache. Serious side effects are rare but can include allergic reactions and Clostridium difficile infection.
Related Terms
- Antibiotic
- Urinary tract infection
- Escherichia coli
- Enterococcus faecalis
- Multidrug-resistant
- Nausea
- Diarrhea
- Headache
- Allergic reaction
- Clostridium difficile infection
External links
- Medical encyclopedia article on Fosfomycin
- Wikipedia's article - Fosfomycin
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski