Sulfamethoxazole
Sulfamethoxazole
Sulfamethoxazole (pronounced sul-fa-meth-ox-a-zole) is a type of antibiotic that belongs to the class of drugs known as sulfonamides.
Etymology
The term "Sulfamethoxazole" is derived from three parts: "sulfa" referring to its sulfonamide group, "meth" indicating a methyl group, and "oxazole" denoting the presence of an oxazole ring in its chemical structure.
Usage
Sulfamethoxazole is commonly used in combination with trimethoprim, a dihydrofolate reductase inhibitor, to treat a variety of bacterial infections. This combination is known as co-trimoxazole and is used to treat conditions such as urinary tract infections, bronchitis, and pneumocystis pneumonia.
Mechanism of Action
Sulfamethoxazole works by inhibiting the synthesis of folic acid in bacteria, which is necessary for the production of essential proteins and DNA. By blocking this process, the drug prevents the bacteria from growing and multiplying.
Side Effects
Common side effects of sulfamethoxazole include nausea, vomiting, loss of appetite, and skin rash. In rare cases, it can cause serious side effects such as anemia, hepatitis, and Stevens-Johnson syndrome.
Related Terms
- Antibiotic
- Sulfonamides
- Trimethoprim
- Co-trimoxazole
- Urinary tract infections
- Bronchitis
- Pneumocystis pneumonia
- Folic acid
- Anemia
- Hepatitis
- Stevens-Johnson syndrome
External links
- Medical encyclopedia article on Sulfamethoxazole
- Wikipedia's article - Sulfamethoxazole
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