Clavulanic acid
Clavulanic Acid
Clavulanic acid (pronounced kla-vyoo-LAN-ik AS-id) is a beta-lactamase inhibitor that is frequently combined with penicillin group antibiotics to combat antibiotic resistance.
Etymology
The term "clavulanic acid" is derived from the Latin clavus, meaning "nail" or "club", which is a reference to the shape of the molecule. The suffix "-ic acid" is a standard chemical nomenclature indicating a compound that can donate a proton or accept an electron pair in reactions.
Usage
Clavulanic acid is used in combination with a penicillin group antibiotic to overcome antibiotic resistance in bacteria that secrete beta-lactamase, which otherwise inactivates most penicillins. The most commonly used combination is with amoxicillin (co-amoxiclav, trade names include Augmentin).
Related Terms
See Also
External links
- Medical encyclopedia article on Clavulanic acid
- Wikipedia's article - Clavulanic acid
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