Protein synthesis inhibitor
Protein Synthesis Inhibitor
A Protein Synthesis Inhibitor (pronunciation: proh-teen sin-thuh-sis in-hib-i-tor) is a substance that stops or slows down the process of protein synthesis.
Etymology
The term "Protein Synthesis Inhibitor" is derived from three words. "Protein" comes from the Greek word "proteios", meaning "primary" or "in the lead". "Synthesis" is derived from the Greek word "synthesis" meaning "composition". "Inhibitor" comes from the Latin word "inhibere" meaning "to hold in".
Function
Protein Synthesis Inhibitors function by preventing the ribosome from translating mRNA into protein. This can occur at various stages of the protein synthesis process, including initiation, elongation, and termination.
Types
There are several types of Protein Synthesis Inhibitors, including aminoglycosides, tetracyclines, and macrolides. Each of these types inhibits protein synthesis in a different way.
Aminoglycosides
Aminoglycosides are a type of antibiotic that inhibit protein synthesis by binding to the 30S subunit of the bacterial ribosome.
Tetracyclines
Tetracyclines are another type of antibiotic that inhibit protein synthesis. They do this by binding to the 30S subunit of the bacterial ribosome and preventing the attachment of tRNA.
Macrolides
Macrolides inhibit protein synthesis by binding to the 50S subunit of the bacterial ribosome and preventing the translocation of peptidyl-tRNA.
Related Terms
External links
- Medical encyclopedia article on Protein synthesis inhibitor
- Wikipedia's article - Protein synthesis inhibitor
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