Sulfanilamide
Sulfanilamide is a sulfonamide antibacterial medication. It was one of the first systematic antibiotics to be used and was widely used in the second half of the 20th century. It is an intermediate in the synthesis of other pharmaceutical drugs such as sulfamethoxazole and sulfapyridine.
History
Sulfanilamide was first synthesized by the Austrian chemist Paul Gelmo in 1908 and was used in the dye industry. Its antibacterial properties were discovered by the German pathologist and bacteriologist Gerhard Domagk. He was awarded the Nobel Prize in Physiology or Medicine in 1939 for the discovery of the antibacterial effects of Prontosil, a red dye which is metabolized in the body to release sulfanilamide.
Mechanism of action
Sulfanilamide works by inhibiting the enzyme dihydropteroate synthase. This enzyme is needed in the synthesis of folic acid, which is essential for the growth and multiplication of bacteria. By inhibiting this enzyme, sulfanilamide prevents the bacteria from synthesizing folic acid, thereby stopping their growth.
Side effects
Like all medications, sulfanilamide can cause side effects. These can include nausea, vomiting, diarrhea, and allergic reactions. In rare cases, it can cause serious side effects such as Stevens-Johnson syndrome, a severe skin reaction, and hemolytic anemia, a condition in which red blood cells are destroyed faster than they can be made.
See also
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
