Sulfadimethoxine

From Food & Medicine Encyclopedia

Sulfadimethoxine is a long-lasting sulfonamide antimicrobial medication used in veterinary medicine. It is used to treat many infections, including respiratory, urinary tract, enteric, and soft tissue infections.

Pharmacology[edit]

Sulfadimethoxine inhibits bacterial synthesis of folic acid, which is essential for the growth and reproduction of bacteria. It is a competitive inhibitor of para-aminobenzoic acid (PABA), which is required by bacteria to synthesize folic acid.

Veterinary Use[edit]

In veterinary medicine, sulfadimethoxine is used to treat a variety of infections. It is commonly used in the treatment of coccidiosis, a parasitic disease of the intestinal tract. It is also used to treat fowl cholera, avian malaria, and infectious coryza in poultry.

Side Effects[edit]

Like other sulfonamides, sulfadimethoxine can cause a variety of side effects. These can include anemia, leukopenia, thrombocytopenia, and hypersensitivity reactions. In rare cases, it can cause crystalluria, which can lead to kidney damage.

Regulatory Status[edit]

In the United States, sulfadimethoxine is approved by the Food and Drug Administration (FDA) for use in chickens, turkeys, and dogs. It is not approved for use in humans.

See Also[edit]

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