Sulfasalazine

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Sulfasalazine

Sulfasalazine (pronounced sul-fa-SAL-a-zeen) is a drug used in the treatment of rheumatoid arthritis, ulcerative colitis, and Crohn's disease.

Etymology

The term "Sulfasalazine" is derived from its chemical structure, which consists of a sulfapyridine and salicylic acid (a compound related to aspirin) linked together.

Usage

Sulfasalazine is classified as a disease-modifying antirheumatic drug (DMARD). It works by reducing inflammation and swelling in the joints, thereby reducing pain and preventing further joint damage in patients with rheumatoid arthritis. In the case of ulcerative colitis and Crohn's disease, it helps to reduce inflammation in the gut, thereby reducing symptoms and preventing flare-ups.

Related Terms

  • Rheumatoid arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet.
  • Ulcerative colitis: A chronic, inflammatory bowel disease that causes inflammation in the digestive tract.
  • Crohn's disease: A type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.
  • Disease-modifying antirheumatic drug (DMARD): A type of drug used in the treatment of rheumatoid arthritis that slows or stops the immune system from attacking the joints.

Side Effects

Like all medications, Sulfasalazine can cause side effects. Common side effects include nausea, vomiting, stomach pain, and loss of appetite. More serious side effects can include liver problems, severe skin reactions, and a decrease in the number of blood cells produced by the body.

Precautions

Before starting treatment with Sulfasalazine, patients should inform their doctor if they have a history of liver disease, kidney disease, or a blood disorder. It is also important to inform the doctor of any other medications being taken, as Sulfasalazine can interact with other drugs.

External links

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