Piperacillin-tazobactam
Piperacillin-tazobactam
Piperacillin-tazobactam (pronunciation: pie-per-a-sill-in taz-o-bactam) is a combination medication containing the antibiotic piperacillin and the beta-lactamase inhibitor tazobactam.
Etymology
The term "piperacillin" is derived from the Latin piper, meaning "pepper", and acillin, a common suffix for penicillin derivatives. "Tazobactam" is a coined term, with no known etymology.
Usage
Piperacillin-tazobactam is used to treat a variety of bacterial infections, including pneumonia, skin infections, and intra-abdominal infections. The tazobactam component inhibits the action of beta-lactamase enzymes, thereby preventing the degradation of piperacillin and enhancing its antibacterial activity.
Dosage and Administration
The dosage of piperacillin-tazobactam varies depending on the type and severity of the infection, as well as the patient's age and overall health status. It is typically administered intravenously in a hospital setting.
Side Effects
Common side effects of piperacillin-tazobactam include nausea, diarrhea, and skin rash. More serious side effects, such as anaphylaxis and Clostridium difficile-associated diarrhea, can also occur.
Related Terms
- Antibiotic
- Beta-lactamase inhibitor
- Bacterial infections
- Pneumonia
- Skin infections
- Intra-abdominal infections
- Nausea
- Diarrhea
- Skin rash
- Anaphylaxis
- Clostridium difficile-associated diarrhea
External links
- Medical encyclopedia article on Piperacillin-tazobactam
- Wikipedia's article - Piperacillin-tazobactam
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