11α-Hydroxyprogesterone

From Food & Medicine Encyclopedia

What is 11α-Hydroxyprogesterone?[edit]

11α-Hydroxyprogesterone
  • It is an endogenous steroid and metabolite of progesterone.
  • IUPAC Name: (8S,9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • InChI: InChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18+,19+,20-,21+/m0/s1
  • InChI Key: BFZHCUBIASXHPK-QJSKAATBSA-N
  • Canonical SMILES: CC(=O)C1CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C
  • Isomeric SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(C[C@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C
  • Molecular formula: C21H30O3
  • Molecular weight: 330.5 g·mol−1
  • Synonyms:
  1. 80-75-1
  2. Progesterone, 11alpha-hydroxy-
  3. 11alpha-hydroxypregn-4-ene-3,20-dione
  4. (11alpha)-11-hydroxypregn-4-ene-3,20-dione
  5. 11-alpha-HYDROXYPROGESTERONE
  6. 11-alpha-Hydroxypregn-4-ene-3,20-dione
  7. 4-Pregnen-11alpha-ol-3,20-dione
  8. U 0384
  9. MLS000028508
  10. MLS001074094
  11. CHEMBL1563246
  12. CHEBI:16076
  13. (8S,9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  14. 11-Hydroxyprogesterone
  15. SMR000058261
  16. Pregn-4-ene-3,20-dione, 11alpha-hydroxy- (8CI)
  17. Pregn-4-ene-3,20-dione, 11-hydroxy-, (11alpha)- (9CI)
  18. 11 -hydroxyprogesterone
  19. NSC 3350
  20. 11.alpha.-Hydroxyprogesterone
  21. EINECS 201-306-9
  22. stetaderm
  23. Progesterone, 11.alpha.-hydroxy-
  24. 11alpha-Hydroxy-4-pregnene-3,20-dione
  25. Pregn-4-ene-3,20-dione, 11.alpha.-hydroxy-
  26. Opera_ID_1692
  27. bmse000529
  28. 11|A-Hydroxy Progesterone
  29. Pregn-4-ene-3,20-dione, 11-hydroxy-, (11.alpha.)-
  30. 11alpha-hydroxy progesterone
  31. 11I+/--Hydroxyprogesterone
  32. SCHEMBL985222
  33. CHEMBL307710
  34. DTXSID10861644
  35. HMS2235P13
  36. 17-Acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  37. ZINC3881614
  38. 2562AC
  39. BBL029911
  40. BDBM50025438
  41. BDBM50442536
  42. LMST02030184
  43. MFCD00003652
  44. STK801965
  45. AKOS005622663
  46. 11-Hydroxypregn-4-ene-3,20-dione #
  47. 4-Pregnen-11.alpha.-ol-3,20-dione
  48. AS-10164
  49. Q27098366
  50. C7FA0F45-BECD-4648-A1F3-7389ED9246EE
  51. (8S,10R,11R,13S,17S)-17-Acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  52. (9S,10R,11R,13S,14S,17S)-17-acetyl-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

<ref>National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 92730, 11alpha-Hydroxyprogesterone. Retrieved August 2, 2021 from https://pubchem.ncbi.nlm.nih.gov/compound/11alpha-Hydroxyprogesterone.</ref>

References[edit]

Endogenous steroids
Precursors
Corticosteroids
Sex steroids
Androgens
Estrogens
* Estranes: Estetrol
Progestogens
Neurosteroids
Others


Androgen receptor modulators
AR
Agonists
* Testosterone derivatives: 4-Androstenediol
SARMs
Antagonists
* Steroidal: 7α-Thioprogesterone
GPRC6A


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