Pregnenolone sulfate

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Pregnenolone sulfate

Pregnenolone sulfate (pronunciation: preɡˈnɛnəˌloʊn ˈsʌlfeɪt) is a steroid sulfate that is involved in the steroidogenesis of numerous steroids. It is derived from pregnenolone, a steroid hormone that plays a key role in the production of other steroid hormones.

Etymology

The term "pregnenolone" is derived from "pregnane", a term used to describe the skeleton structure common to all naturally occurring steroids, and "ol", a suffix used in organic chemistry to form names of hydrocarbons containing the hydroxyl (-OH) group. The "sulfate" part of the name refers to the sulfate group (-SO4) attached to the pregnenolone molecule.

Function

Pregnenolone sulfate is a neurosteroid, which means it is synthesized in the brain and affects neuronal functioning. It is known to modulate several neurotransmitter systems, including the GABA and NMDA receptor systems. It also plays a role in memory and learning processes.

Related Terms

  • Steroidogenesis: The biological process by which steroids are generated from cholesterol.
  • Neurosteroid: Steroids synthesized in the brain that are involved in a wide range of functions.
  • GABA: A neurotransmitter that inhibits or reduces the activity of nerve cells within the nervous system.
  • NMDA receptor: A type of glutamate receptor that is important for controlling synaptic plasticity and memory function.

See Also

External links

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