Ethisterone

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Ethisterone

Ethisterone (pronounced: eh-this-te-rone), also known as pregneninolone, is a progestin medication which was discovered in 1938 and was the first progestin to be marketed. It is an orally active progestogen which was used for the treatment of gynecological disorders but is now rarely used as it has been superseded by newer drugs.

Etymology

The term "Ethisterone" is derived from the Greek words "ethos" meaning character, and "sterone" which is a suffix used in chemical nomenclature to denote a steroid.

Pharmacology

Ethisterone is a synthetic progestogen and is a derivative of testosterone. It works by suppressing the secretion of luteinizing hormone and follicle-stimulating hormone from the pituitary gland, thereby inhibiting ovulation and thus preventing pregnancy.

Medical Uses

Ethisterone was used for the treatment of various gynecological disorders such as menorrhagia, dysmenorrhea, and endometriosis. It was also used as a component of hormone replacement therapy for menopausal symptoms.

Side Effects

The side effects of Ethisterone are similar to those of other progestogens and may include weight gain, breast tenderness, nausea, and irregular menstrual bleeding. In rare cases, it may cause jaundice or liver disease.

Related Terms

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