Trestolone enanthate
Overview
Trestolone Enanthate is a synthetic androgen and anabolic steroid (AAS) that is used in medical research and has potential applications in hormone replacement therapy and contraception. It is an esterified form of trestolone, also known as 7_-methyl-19-nortestosterone (MENT), which is a potent androgen receptor agonist.
Chemical Properties
Trestolone Enanthate is characterized by the addition of an enanthate ester to the 17_-hydroxyl group of trestolone. This modification increases the lipophilicity of the compound, allowing for a prolonged release and action when administered via intramuscular injection. The chemical structure of Trestolone Enanthate is depicted in the adjacent image.
Mechanism of Action
Trestolone Enanthate acts by binding to the androgen receptor, mimicking the effects of natural testosterone. It promotes the development and maintenance of male secondary sexual characteristics and has significant anabolic effects, which include the stimulation of muscle growth and bone density.
Clinical Applications
Trestolone Enanthate is primarily investigated for its potential use in male contraception. It suppresses spermatogenesis by inhibiting the secretion of gonadotropins from the pituitary gland, thereby reducing testosterone production in the testes. Additionally, it is being studied for its use in hormone replacement therapy for men with hypogonadism.
Side Effects
As with other anabolic steroids, the use of Trestolone Enanthate can lead to side effects such as acne, gynecomastia, hypertension, and alterations in lipid profiles. Long-term use may also affect liver function and increase the risk of cardiovascular disease.
Administration
Trestolone Enanthate is typically administered via intramuscular injection. The dosing regimen depends on the specific clinical application and the individual patient's response to therapy.
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