Estrone
Estrone
Estrone (pronounced: es-trone), also known as E1 and oestrone, is one of the three naturally occurring estrogens, alongside estradiol and estriol. It is a steroid hormone produced primarily by the ovaries and in smaller amounts by the adrenal glands, testes, and fatty tissue.
Etymology
The term "estrone" is derived from the Greek oistros, meaning "gadfly, breeze, sting, mad" and one, a suffix used in chemistry to denote a ketone. The name reflects the hormone's role in the menstrual cycle and reproduction.
Function
Estrone is primarily a metabolic intermediate in the production of estradiol, and to a lesser extent, estriol. It is considered a weaker estrogen, as it is less potent in stimulating the growth of the endometrium. However, in postmenopausal women, estrone becomes the primary form of estrogen in the body.
Related Terms
- Estrogen: A group of steroid hormones that promote the development and maintenance of female characteristics of the body.
- Estradiol: The most potent and prevalent estrogen hormone in the body.
- Estriol: The weakest of the three natural estrogens.
- Endometrium: The mucous membrane lining the uterus, which thickens during the menstrual cycle in preparation for possible implantation of an embryo.
See Also
External links
- Medical encyclopedia article on Estrone
- Wikipedia's article - Estrone
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