Norethisterone

Norethisterone

Norethisterone (pronounced: nor-eth-in-drohn), also known as norethindrone in the United States, is a synthetic progestogen that is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.

Etymology

The term "Norethisterone" is derived from the words "nor-", a prefix used in organic chemistry to denote a structure lacking a carbon atom, and "ethisterone", a progestin that is related to the naturally occurring hormone progesterone.

Medical Uses

Norethisterone is primarily used in contraceptive pills, specifically in combined oral contraceptive pills and progestogen-only pills. It is also used in menopausal hormone therapy for the treatment of menopausal symptoms. In addition, it is used to treat gynecological disorders such as endometriosis, menorrhagia (heavy menstrual bleeding), and amenorrhea (absence of menstrual periods).

Pharmacology

Norethisterone is a synthetic progestogen, meaning it mimics the effects of the natural hormone progesterone. It works by preventing ovulation, altering the cervical mucus to make it difficult for sperm to reach the egg, and changing the lining of the uterus to prevent a fertilized egg from implanting.

Side Effects

Common side effects of norethisterone include menstrual irregularities, headache, nausea, breast tenderness, mood changes, acne, and weight gain. More serious side effects can include blood clots, liver problems, and allergic reactions.

Related Terms

• Progestogen
• Contraceptive pill
• Endometriosis
• Menorrhagia
• Amenorrhea

External links

• Medical encyclopedia article on Norethisterone
• Wikipedia's article - Norethisterone

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