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Chloride Ion

Structure of the chloride ion.

The chloride ion is the anion (negatively charged ion) Cl_. It is formed when the element chlorine gains an electron or when a compound containing chloride is dissolved in water or another polar solvent. Chloride salts such as sodium chloride are often very soluble in water. It is an essential electrolyte located in all body fluids responsible for maintaining acid/base balance, transmitting nerve impulses, and regulating fluid in and out of cells.

Properties

Chloride is a monovalent ion, meaning it carries a single negative charge. It is the conjugate base of the weak acid hydrochloric acid (HCl). Chloride ions are colorless in solution and have a high solubility in water. They are also found in many other chemical compounds, including potassium chloride, calcium chloride, and magnesium chloride.

Biological Role

Chloride ions play a crucial role in the physiology of living organisms. They are involved in maintaining the osmotic pressure of body fluids and are a key component of the electrolyte balance. Chloride is also essential for the production of gastric acid in the stomach, which is necessary for digestion.

In the human body, chloride is absorbed in the intestines and excreted primarily by the kidneys. The balance of chloride ions is maintained by the renal system, and any imbalance can lead to conditions such as hypochloremia or hyperchloremia.

Industrial Uses

Chloride ions are used in a variety of industrial applications. They are used in the production of polyvinyl chloride (PVC), a common plastic. Chloride is also used in the production of bleach, disinfectants, and in the chlorination of drinking water to kill harmful bacteria.

Environmental Impact

Chloride ions can be found in natural water sources, and their concentration can be increased by human activities such as the use of road salt and the discharge of industrial effluents. High levels of chloride in water can be harmful to aquatic life and can lead to the corrosion of infrastructure.

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Contributors: Prab R. Tumpati, MD