Dimethyltrienolone

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Dimethyltrienolone

Chemical structure of Dimethyltrienolone

Dimethyltrienolone is a potent anabolic steroid that is derived from nandrolone. It is known for its high androgen receptor binding affinity and significant anabolic effects. Dimethyltrienolone is a synthetic androgen and anabolic steroid (AAS) that has been studied for its potential use in medicine and sports.

Chemical Properties

Dimethyltrienolone is chemically related to trenbolone, another powerful anabolic steroid. It is characterized by the addition of two methyl groups at the 17_ position, which enhances its oral bioavailability and resistance to metabolism. The chemical structure of Dimethyltrienolone is depicted in the adjacent image.

Mechanism of Action

Dimethyltrienolone exerts its effects by binding to the androgen receptor, which leads to the activation of gene transcription and subsequent protein synthesis. This results in increased muscle mass and strength. The compound is known for its strong anabolic effects, which are significantly greater than those of testosterone.

Medical and Non-Medical Use

While Dimethyltrienolone has been studied for potential therapeutic applications, such as in the treatment of muscle wasting and osteoporosis, it has not been approved for medical use due to its high potential for hepatotoxicity and other adverse effects. In the realm of sports, it is considered a performance-enhancing drug and is banned by most sporting organizations.

Side Effects

The use of Dimethyltrienolone is associated with several side effects, primarily due to its potent androgenic activity. These include:

Due to these risks, its use is generally discouraged outside of controlled research settings.

Related Compounds

Dimethyltrienolone is related to other anabolic steroids such as trenbolone, nandrolone, and methandrostenolone. These compounds share similar mechanisms of action but differ in their potency and side effect profiles.

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Contributors: Prab R. Tumpati, MD