Androstenediol

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Androstenediol

Androstenediol (pronunciation: an-dro-sten-e-diol), also known as Androdiol, is a steroid hormone produced in the adrenal glands and the gonads as an intermediate step in the biochemical pathway that produces the androgen testosterone and the estrogens estrone and estradiol.

Etymology

The term "Androstenediol" is derived from the Greek words "Andro" meaning man, "stene" meaning narrow or slender, and "diol" a chemical term referring to a certain type of alcohol.

Production and Function

Androstenediol is produced in the adrenal glands and the gonads through the conversion of dehydroepiandrosterone (DHEA). This process is catalyzed by the enzyme 17β-hydroxysteroid dehydrogenase. Androstenediol is then further converted into testosterone, a primary male sex hormone, or into estrone and estradiol, primary female sex hormones.

Related Terms

  • Androgen: A type of hormone that plays a role in male traits and reproductive activity. Androstenediol is a type of androgen.
  • Testosterone: A hormone produced by the human body. It’s mainly produced in men by the testicles. Androstenediol is a precursor to testosterone.
  • Estrone and Estradiol: Two forms of estrogen, a hormone that plays a key role in the female reproductive system. Androstenediol can be converted into these hormones.
  • 17β-hydroxysteroid dehydrogenase: An enzyme that catalyzes the conversion of DHEA to androstenediol.

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