Methandriol diacetate

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Methandriol Diacetate

Chemical structure of Methandriol diacetate

Methandriol diacetate is a synthetic anabolic-androgenic steroid (AAS) and a derivative of methandriol. It is an esterified form of methandriol, specifically the diacetate ester, which is designed to enhance the pharmacokinetic properties of the parent compound.

Chemical Properties

Methandriol diacetate is characterized by its chemical structure, which includes the diacetate ester. This modification increases the lipophilicity of the molecule, allowing for a more prolonged release and action when administered. The chemical structure of methandriol diacetate is depicted in the adjacent image.

Pharmacology

Methandriol diacetate acts as an agonist of the androgen receptor, similar to other anabolic steroids. It promotes protein synthesis and muscle growth, making it popular in bodybuilding and athletic contexts. The esterification with diacetate allows for a slower release into the bloodstream, providing a more sustained effect compared to non-esterified forms.

Administration

Methandriol diacetate is typically administered via intramuscular injection. The ester form allows for less frequent dosing compared to non-esterified methandriol, which is beneficial for maintaining stable blood levels of the drug.

Side Effects

As with other anabolic steroids, methandriol diacetate can cause a range of side effects. These may include androgenic effects such as acne, increased body hair, and potential virilization in females. It may also affect the cardiovascular system, liver function, and endocrine system.

Legal Status

The legal status of methandriol diacetate varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and health risks associated with non-medical use.

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Contributors: Prab R. Tumpati, MD