Oxymesterone
Oxymesterone
Oxymesterone is a synthetic anabolic steroid derived from testosterone. It was developed in the 1950s and has been used in the treatment of various medical conditions, although its use has declined due to the development of newer agents with more favorable safety profiles.
Chemical Properties
Oxymesterone is chemically known as 17_-methyl-4,5_-epoxy-4-androsten-3-one. It is a 17_-alkylated derivative of testosterone, which allows it to be administered orally. The presence of the epoxy group at the 4,5 position is a distinguishing feature of this compound.
Mechanism of Action
As an anabolic steroid, oxymesterone exerts its effects by binding to the androgen receptors in various tissues. This binding leads to an increase in protein synthesis, nitrogen retention, and muscle mass. It also has effects on the central nervous system, which can influence mood and behavior.
Medical Uses
Oxymesterone has been used in the past to treat conditions such as hypogonadism, delayed puberty in males, and certain types of anemia. Its anabolic properties were also utilized in the treatment of muscle wasting conditions.
Side Effects
The use of oxymesterone, like other anabolic steroids, can lead to a range of side effects. These include hepatotoxicity, cardiovascular disease risk, gynecomastia, and testicular atrophy. Due to its 17_-alkylated structure, it is particularly associated with liver toxicity.
Legal Status
In many countries, oxymesterone is classified as a controlled substance due to its potential for abuse and adverse health effects. It is not commonly prescribed today, with preference given to other treatments with better safety profiles.
Related Compounds
Oxymesterone is related to other anabolic steroids such as oxandrolone, stanozolol, and methandrostenolone. These compounds share similar mechanisms of action but differ in their specific chemical structures and side effect profiles.
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