Metribolone

From WikiMD's medical encyclopedia

Metribolone (also known as methyltrienolone or R1881) is a potent, non-aromatizable androgen that is used in scientific research and has been sold online as a designer steroid. Metribolone is an oral steroid and is one of the strongest available on the market, it is also one of the most hepatotoxic and is not recommended for practical use.

History

Metribolone was first described in 1965. It was immediately recognized as an extraordinarily potent anabolic agent, significantly more potent than the reference anabolic steroid in that study, fluoxymesterone. However, its potential for liver toxicity was also quickly realized.

Pharmacology

As an AAS, metribolone is an agonist of the androgen receptor (AR), similarly to androgens like testosterone and dihydrotestosterone (DHT). It is one of the most potent AAS to have ever been synthesized, with 120–300 times the oral anabolic potency and 60–70 times the androgenic potency of methyltestosterone, and 12 times the oral anabolic potency and 2.5 times the androgenic potency of oxymetholone.

Side Effects

Metribolone is considered one of the most toxic steroids. It is both highly hepatotoxic and capable of causing damage to the liver. It also has potential side effects in many other areas, including cardiovascular complications, and potential direct neurological and mental changes. It is so dangerous that it is often used in research studies to induce damage to the liver as it is so reliably toxic.

Legal Status

In the United States, metribolone is classified as a Schedule III controlled substance under federal regulation, under the Controlled Substances Act. It is also banned by many sporting organizations, including the International Olympic Committee.

See Also

FlattenedRoundPills.jpg
This article is a stub related to pharmacology. You can help WikiMD by expanding it!


Stub icon
   This article is a medical stub. You can help WikiMD by expanding it!



Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Transform your life with W8MD's budget GLP-1 injections from $125.

W8mdlogo.png
W8MD weight loss doctors team

W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:

NYC weight loss doctor appointments

Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.

Linkedin_Shiny_Icon Facebook_Shiny_Icon YouTube_icon_(2011-2013) Google plus


Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD