Testosterone (patch)

Testosterone transdermal patches are a form of hormone replacement therapy used to treat adult men experiencing symptoms of low testosterone due to hypogonadism. Hypogonadism is a condition where the body fails to produce sufficient levels of testosterone due to issues with the testicles, pituitary gland, or hypothalamus. These patches are designed to deliver testosterone directly through the skin, thus supplementing the body's natural hormone production.

Overview

Testosterone is a critical hormone in the male body, responsible for the growth and development of male sexual organs and maintaining typical male characteristics. When testosterone levels are low, men can experience a range of symptoms that can affect their physical health and quality of life.

Indications for Use

Transdermal testosterone patches are indicated for men who have low testosterone levels as a result of medical conditions such as:

• Disorders of the testicles
• Dysfunction of the pituitary gland
• Complications within the hypothalamus

Before beginning treatment, healthcare providers conduct lab tests to confirm low testosterone levels are due to hypogonadism and not simply a result of aging.

Usage

Patients prescribed with testosterone transdermal patches should apply them according to their doctor's instructions, typically once a day on specific parts of the body. The patch steadily releases testosterone into the bloodstream through the skin.

Mechanism of Action

The mechanism of action for testosterone transdermal patches involves the absorption of testosterone through the skin and its distribution into the bloodstream, where it can exert its effects on the body, similar to naturally produced testosterone.

Contraindications

Testosterone patches should not be used in men with:

• Low testosterone due solely to aging ('age-related hypogonadism')
• Breast cancer
• Known or suspected prostate cancer

Drug Classification

Testosterone is classified as an androgenic hormone under the class of medications called androgens.

Side Effects

Like all medications, testosterone patches can cause side effects. Some may experience skin irritation at the site of application, while others might have more systemic effects due to increased testosterone levels.

Considerations and Precautions

Patients must follow their healthcare provider's guidance on using testosterone patches. They should be aware of potential side effects and the importance of regular monitoring of testosterone levels throughout treatment.

Brand Names and Variations

While there are various brand names for testosterone patches, one known brand was Intrinsa®, which was specifically designed to treat female sexual dysfunction but is no longer marketed.

• Androderm®
• Testoderm®

See Also

• Hormone Replacement Therapy
• Hypogonadism
• Androgens
• Pituitary Gland
• Hypothalamus
• Testicles
• Male sexual dysfunction

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