Gestonorone caproate
Gestonorone caproate is a progestin medication that is used in hormone therapy and for the treatment of gynecological disorders. It is a synthetic derivative of progesterone and is known for its potent progestogenic activity.
Chemical Structure and Properties
Gestonorone caproate, also known as 17α-hydroxy-19-norprogesterone caproate, is a steroidal progestin. Its chemical structure is characterized by the presence of a caproate ester at the 17α position of the molecule. This modification enhances its duration of action when administered.
Mechanism of Action
As a progestin, gestonorone caproate works by binding to the progesterone receptors in the body. This binding mimics the effects of natural progesterone, leading to changes in the endometrium and inhibition of ovulation. It also has antiestrogenic effects, which can be beneficial in treating certain hormone-dependent conditions.
Medical Uses
Gestonorone caproate is primarily used in the treatment of various gynecological conditions, including:
- Endometriosis
- Dysfunctional uterine bleeding
- Menstrual disorders
- As part of hormone replacement therapy (HRT) in menopause
Administration and Dosage
Gestonorone caproate is typically administered via intramuscular injection. The dosage and frequency of administration depend on the specific condition being treated and the patient's response to the therapy.
Side Effects
Common side effects of gestonorone caproate may include:
Contraindications
Gestonorone caproate should not be used in individuals with:
- Known or suspected breast cancer
- Active thromboembolic disorders
- Severe liver disease
- Known hypersensitivity to the drug
See Also
References
External Links
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