SNC-80
SNC-80 is a synthetic compound that acts as a selective agonist for the delta-opioid receptor. It is primarily used in scientific research to study the effects and potential therapeutic applications of delta-opioid receptor activation.
Chemical Properties
SNC-80 is classified as a non-peptide delta-opioid receptor agonist. Its chemical structure allows it to selectively bind to and activate delta-opioid receptors, which are one of the three main types of opioid receptors in the body, the others being mu and kappa receptors.
Pharmacology
SNC-80 has been shown to produce a range of effects in animal models, including analgesia, antidepressant-like effects, and anxiolytic effects. Unlike many other opioid receptor agonists, SNC-80 does not produce significant respiratory depression, which is a major side effect of mu-opioid receptor agonists like morphine.
Mechanism of Action
SNC-80 exerts its effects by binding to delta-opioid receptors, which are G-protein coupled receptors (GPCRs). Activation of these receptors leads to a cascade of intracellular events that result in the modulation of neurotransmitter release and neuronal excitability.
Research Applications
SNC-80 is widely used in preclinical research to explore the potential therapeutic benefits of delta-opioid receptor activation. Studies have investigated its potential in treating conditions such as chronic pain, depression, and anxiety disorders.
Side Effects and Limitations
While SNC-80 has shown promise in preclinical studies, it also has limitations. Some studies have reported that it can produce convulsions at high doses, which limits its therapeutic window. Additionally, the development of tolerance to its effects has been observed in some animal models.
See Also
References
External Links
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Contributors: Prab R. Tumpati, MD