Androgen receptor antagonist

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Androgen receptor antagonist
TermAndrogen receptor antagonist
Short definitionAndrogen receptor antagonist (AN-droh-jen reh-SEP-ter an-TA-guh-nist) substance that prevents androgens (male sex hormones) from attaching to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells and cells in some other tissues. Preventing this binding blocks the action of these hormones in the body. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Androgen receptor antagonist - (pronounced) (AN-droh-jen reh-SEP-ter an-TA-guh-nist) substance that prevents androgens (male sex hormones) from attaching to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells and cells in some other tissues. Preventing this binding blocks the action of these hormones in the body. Treatment with androgen receptor antagonists can prevent the growth of prostate cancer cells. Examples of androgen receptor antagonists used to treat prostate cancer are apalutamide, bicalutamide, darolutamide, enzalutamide, flutamide, and nilutamide. Also called androgen receptor blockers and antiandrogen

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