Pancreatitis: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Pancreatitis
| image          = [[File:Illu_pancrease.svg|alt=Diagram of the pancreas]]
| caption        = Diagram of the [[pancreas]]
| field          = [[Gastroenterology]]
| symptoms        = [[Abdominal pain]], [[nausea]], [[vomiting]], [[fever]]
| complications  = [[Pancreatic necrosis]], [[pseudocyst]], [[diabetes mellitus]], [[pancreatic cancer]]
| onset          = Sudden (acute) or gradual (chronic)
| duration        = Varies (acute: days to weeks, chronic: months to years)
| causes          = [[Gallstones]], [[alcohol consumption]], [[hypertriglyceridemia]], [[medications]]
| risks          = [[Alcohol use disorder]], [[smoking]], [[family history]]
| diagnosis      = [[Blood tests]], [[imaging studies]] ([[CT scan]], [[MRI]], [[ultrasound]])
| differential    = [[Peptic ulcer disease]], [[cholecystitis]], [[mesenteric ischemia]]
| treatment      = [[Fasting]], [[IV fluids]], [[pain management]], [[antibiotics]] (if infected)
| medication      = [[Analgesics]], [[enzyme supplements]] (for chronic)
| prognosis      = Varies (depends on severity and complications)
| frequency      = 4.9–35 per 100,000 annually (acute)
| deaths          = 1.6 per 100,000 annually (acute)
}}
'''Pancreas''' is a long, flat gland located in the abdominal cavity, behind the stomach. It is a vital organ that plays a crucial role in the digestive system and endocrine system. The pancreas produces enzymes that help to break down food and hormones, such as insulin and glucagon, that help to regulate glucose levels in the blood.
'''Pancreas''' is a long, flat gland located in the abdominal cavity, behind the stomach. It is a vital organ that plays a crucial role in the digestive system and endocrine system. The pancreas produces enzymes that help to break down food and hormones, such as insulin and glucagon, that help to regulate glucose levels in the blood.
[[File:Illu pancrease.svg|thumb]]
== Structure and Location ==
== Structure and Location ==
The pancreas is an elongated organ, approximately 12-15 cm long, and is divided into four parts: the head, neck, body, and tail. The head of the pancreas is located near the duodenum, while the tail extends towards the spleen. It is positioned behind the stomach and is surrounded by several important organs and blood vessels, including the liver, gallbladder, and small intestine.
The pancreas is an elongated organ, approximately 12-15 cm long, and is divided into four parts: the head, neck, body, and tail. The head of the pancreas is located near the duodenum, while the tail extends towards the spleen. It is positioned behind the stomach and is surrounded by several important organs and blood vessels, including the liver, gallbladder, and small intestine.
== Functions ==
== Functions ==
The pancreas has two main functions: exocrine and endocrine.
The pancreas has two main functions: exocrine and endocrine.
=== Exocrine Function ===
=== Exocrine Function ===
The exocrine function of the pancreas involves the production and secretion of digestive enzymes that aid in the breakdown of food. These enzymes include:
The exocrine function of the pancreas involves the production and secretion of digestive enzymes that aid in the breakdown of food. These enzymes include:
* [[Amylase]]: Breaks down carbohydrates
* [[Amylase]]: Breaks down carbohydrates
* [[Lipase]]: Breaks down fats
* [[Lipase]]: Breaks down fats
* [[Protease]]: Breaks down proteins
* [[Protease]]: Breaks down proteins
These enzymes are secreted into the pancreatic duct, which eventually merges with the bile duct and empties into the duodenum, the first part of the small intestine.
These enzymes are secreted into the pancreatic duct, which eventually merges with the bile duct and empties into the duodenum, the first part of the small intestine.
=== Endocrine Function ===
=== Endocrine Function ===
The endocrine function of the pancreas involves the production and secretion of hormones that regulate blood glucose levels. The pancreas contains small clusters of cells called [[Islets of Langerhans]], which are responsible for producing the following hormones:
The endocrine function of the pancreas involves the production and secretion of hormones that regulate blood glucose levels. The pancreas contains small clusters of cells called [[Islets of Langerhans]], which are responsible for producing the following hormones:
* [[Insulin]]: Lowers blood glucose levels by promoting the uptake and storage of glucose in cells
* [[Insulin]]: Lowers blood glucose levels by promoting the uptake and storage of glucose in cells
* [[Glucagon]]: Raises blood glucose levels by stimulating the release of glucose from stored glycogen in the liver
* [[Glucagon]]: Raises blood glucose levels by stimulating the release of glucose from stored glycogen in the liver
These hormones work together to maintain proper glucose levels in the blood and ensure that the body has a constant supply of energy.
These hormones work together to maintain proper glucose levels in the blood and ensure that the body has a constant supply of energy.
[[File:Pankreatitis_exsudativ_CT_axial.jpg|thumb|Pankreatitis CT]]
[[File:Pankreatitis_exsudativ_CT_axial.jpg|left|thumb|Pankreatitis CT]]
== Pancreatic Disorders ==
== Pancreatic Disorders ==
Several disorders can affect the pancreas, including:
Several disorders can affect the pancreas, including:
* [[Pancreatitis]]: Inflammation of the pancreas, which can be acute or chronic
* [[Pancreatitis]]: Inflammation of the pancreas, which can be acute or chronic
* [[Diabetes]]: A condition characterized by elevated blood glucose levels due to insufficient insulin production (type 1 diabetes) or reduced insulin sensitivity (type 2 diabetes)
* [[Diabetes]]: A condition characterized by elevated blood glucose levels due to insufficient insulin production (type 1 diabetes) or reduced insulin sensitivity (type 2 diabetes)

Latest revision as of 20:49, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Pancreatitis
Diagram of the pancreas
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Abdominal pain, nausea, vomiting, fever
Complications Pancreatic necrosis, pseudocyst, diabetes mellitus, pancreatic cancer
Onset Sudden (acute) or gradual (chronic)
Duration Varies (acute: days to weeks, chronic: months to years)
Types N/A
Causes Gallstones, alcohol consumption, hypertriglyceridemia, medications
Risks Alcohol use disorder, smoking, family history
Diagnosis Blood tests, imaging studies (CT scan, MRI, ultrasound)
Differential diagnosis Peptic ulcer disease, cholecystitis, mesenteric ischemia
Prevention N/A
Treatment Fasting, IV fluids, pain management, antibiotics (if infected)
Medication Analgesics, enzyme supplements (for chronic)
Prognosis Varies (depends on severity and complications)
Frequency 4.9–35 per 100,000 annually (acute)
Deaths 1.6 per 100,000 annually (acute)


Pancreas is a long, flat gland located in the abdominal cavity, behind the stomach. It is a vital organ that plays a crucial role in the digestive system and endocrine system. The pancreas produces enzymes that help to break down food and hormones, such as insulin and glucagon, that help to regulate glucose levels in the blood.

Structure and Location[edit]

The pancreas is an elongated organ, approximately 12-15 cm long, and is divided into four parts: the head, neck, body, and tail. The head of the pancreas is located near the duodenum, while the tail extends towards the spleen. It is positioned behind the stomach and is surrounded by several important organs and blood vessels, including the liver, gallbladder, and small intestine.

Functions[edit]

The pancreas has two main functions: exocrine and endocrine.

Exocrine Function[edit]

The exocrine function of the pancreas involves the production and secretion of digestive enzymes that aid in the breakdown of food. These enzymes include:

These enzymes are secreted into the pancreatic duct, which eventually merges with the bile duct and empties into the duodenum, the first part of the small intestine.

Endocrine Function[edit]

The endocrine function of the pancreas involves the production and secretion of hormones that regulate blood glucose levels. The pancreas contains small clusters of cells called Islets of Langerhans, which are responsible for producing the following hormones:

  • Insulin: Lowers blood glucose levels by promoting the uptake and storage of glucose in cells
  • Glucagon: Raises blood glucose levels by stimulating the release of glucose from stored glycogen in the liver

These hormones work together to maintain proper glucose levels in the blood and ensure that the body has a constant supply of energy.

Pankreatitis CT

Pancreatic Disorders[edit]

Several disorders can affect the pancreas, including:

  • Pancreatitis: Inflammation of the pancreas, which can be acute or chronic
  • Diabetes: A condition characterized by elevated blood glucose levels due to insufficient insulin production (type 1 diabetes) or reduced insulin sensitivity (type 2 diabetes)
  • Pancreatic cancer: A malignant tumor originating in the pancreas
  • Cystic fibrosis: A genetic disorder that affects multiple organs, including the pancreas, and can lead to a reduction in digestive enzyme production

See also[edit]

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