Calcium carbimide
Calcium Carbimide[edit]
Calcium carbimide is a chemical compound used primarily in the treatment of alcohol dependence. It acts as an alcohol deterrent by interfering with the metabolism of alcohol, leading to unpleasant effects when alcohol is consumed.
Mechanism of Action[edit]
Calcium carbimide works by inhibiting the enzyme acetaldehyde dehydrogenase, which is responsible for the breakdown of acetaldehyde, a toxic metabolite of ethanol. When acetaldehyde dehydrogenase is inhibited, acetaldehyde accumulates in the blood, causing symptoms such as flushing, nausea, and palpitations. These symptoms are intended to deter individuals from consuming alcohol.
Clinical Use[edit]
Calcium carbimide is used as part of a comprehensive treatment program for alcohol dependence. It is typically administered orally in tablet form. The drug is most effective when combined with counseling and support groups, as it helps to reinforce the desire to abstain from alcohol.
Side Effects[edit]
Common side effects of calcium carbimide include:
- Flushing
- Nausea
- Vomiting
- Headache
- Dizziness
These side effects are more pronounced when alcohol is consumed. Patients are advised to avoid alcohol completely while taking calcium carbimide.
Contraindications[edit]
Calcium carbimide is contraindicated in individuals with:
- Severe cardiovascular disease
- Severe respiratory disease
- Hypersensitivity to the drug
Related Compounds[edit]
Calcium carbimide is similar in function to disulfiram, another alcohol deterrent. Both drugs work by inhibiting acetaldehyde dehydrogenase, but they differ in their chemical structure and pharmacokinetics.
Related Pages[edit]
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
