Peptic ulcer disease

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Peptic Ulcer Disease

Peptic ulcer disease (PUD), pronounced as /ˈpeptɪk ˈʌlsər dɪˈziːz/, is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus.

Etymology

The term "peptic" derives from the Greek word "peptikos" meaning "pertaining to digestion", and "ulcer" comes from the Latin "ulcus", which means "sore". The term "disease" is derived from the Old French "desaise", meaning "lack of ease".

Symptoms

Symptoms of peptic ulcer disease can include abdominal pain, nausea, vomiting, and weight loss. However, some people may have no symptoms at all.

Causes

Peptic ulcers are usually caused by a bacterial infection with Helicobacter pylori (H. pylori) or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen.

Diagnosis

Diagnosis of peptic ulcer disease is typically confirmed by an endoscopy or an upper gastrointestinal series.

Treatment

Treatment often involves antibiotics to eradicate H. pylori, medications to block or reduce stomach acid, and lifestyle changes such as avoiding certain foods and beverages that can irritate the ulcer.

Related Terms

  • Gastric ulcer: A type of peptic ulcer that develops in the stomach.
  • Duodenal ulcer: A type of peptic ulcer that develops in the first part of the small intestine.
  • Esophageal ulcer: A type of peptic ulcer that develops in the esophagus.
  • Gastroenterology: The branch of medicine focused on the digestive system and its disorders.

External links

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