ATC code L02: Difference between revisions

ATC codes
L Antineoplastic and immunomodulating agents
L01 Antineoplastic agents
L02 Endocrine therapy
L03 Immunostimulants
L04 Immunosuppressants
A B C D G H QI J L M N P R S V (Hover over links to see titles)

ATC code L02 Endocrine therapy is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.<ref>

ATC (Anatomical Therapeutic Chemical Classification System) – Synopsis(link). {{{website}}}. National Institutes of Health.

</ref><ref>

ATC-Klassifikation mit definierten Tagesdosen DDD(link). {{{website}}}. German Institute for Medical Documentation and Information.

</ref> Subgroup L02 is part of the anatomical group L Antineoplastic and immunomodulating agents.<ref>

ATC/DDD Index 2022

code L02(link).

{{{website}}}. WHO Collaborating Centre for Drug Statistics Methodology.

</ref>

Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QL02.<ref>

ATCvet Index 2022

code QL02(link).

{{{website}}}. WHO Collaborating Centre for Drug Statistics Methodology.

</ref>

National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.

L02A Hormones and related agents[edit]

L02AE51 Leuprorelin and bicalutamide

L02AX Other hormones[edit]

L02B Hormone antagonists and related agents[edit]

L02BA Anti-estrogens[edit]

L02BA01 Tamoxifen

L02BA02 Toremifene

L02BA03 Fulvestrant

L02BB Anti-androgens[edit]

L02BB01 Flutamide

L02BB02 Nilutamide

L02BB03 Bicalutamide

L02BB04 Enzalutamide

L02BB05 Apalutamide

L02BG Aromatase inhibitors[edit]

L02BG01 Aminogluthetimide

L02BG02 Formestane

L02BG03 Anastrozole

L02BG04 Letrozole

L02BG05 Vorozole

L02BG06 Exemestane

L02BX Other hormone antagonists and related agents[edit]

L02BX01 Abarelix

L02BX02 Degarelix

L02BX03 Abiraterone

References[edit]

Androgens and antiandrogens

Androgens
(incl. AAS )

AR agonists

* Testosterone derivatives: Androstenediol dipropionate

Dihydrotestosterone derivatives: Androstanolone (stanolone, dihydrotestosterone, DHT)
Androstanolone esters
Bolazine capronate
Drostanolone propionate (dromostanolone propionate)
Epitiostanol
Mepitiostane
Mesterolone
Metenolone acetate (methenolone acetate)
Metenolone enanthate (methenolone enanthate)
Stenbolone acetate

19-Nortestosterone derivatives: Bolandiol dipropionate
Nandrolone esters (e.g., nandrolone decanoate, nandrolone phenylpropionate)
Norclostebol
Norclostebol acetate
Oxabolone cipionate (oxabolone cypionate)
Trenbolone acetate
Trenbolone hexahydrobenzylcarbonate (trenbolone cyclohexylmethylcarbonate)

17α-Alkylated testosterone derivatives: Bolasterone
Calusterone
Chlorodehydromethyltestosterone (CDMT)
Fluoxymesterone
Formebolone
Metandienone (methandienone, methandrostenolone)
Methandriol (methylandrostenediol)
Methandriol bisenanthoyl acetate
Methandriol dipropionate
Methandriol propionate
Methyltestosterone
Methyltestosterone 3-hexyl ether
Oxymesterone
Penmesterol
Tiomesterone (thiomesterone)

17α-Alkylated dihydrotestosterone derivatives: Androisoxazole
Furazabol
Mebolazine (dimethazine)
Mestanolone
Oxandrolone
Oxymetholone
Stanozolol

17α-Alkylated 19-nortestosterone derivatives: Ethylestrenol
Mibolerone
Norethandrolone
Normethandrone (methylestrenolone, normethisterone)
Propetandrol (propethandrol)

17α-Vinyltestosterone derivatives: Norvinisterone (vinylnortestosterone)

17α-Ethynyltestosterone derivatives: Danazol
Gestrinone
Progestins (e.g., ethisterone (ethynyltestosterone), levonorgestrel, norgestrel, norethisterone (norethindrone), lynestrenol, norgestrienone)
Tibolone

Progesterone derivatives: Medroxyprogesterone acetate

Progonadotropins

* Antiestrogens (e.g., tamoxifen, clomifene)

GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin)
Gonadotropins (e.g., LH

, hCG

)

Antiandrogens

AR antagonists

* Steroidal: Abiraterone acetate +niraparib

Steroidogenesis
inhibitors

5α-Reductase	* Alfatradiol Dutasteride Epristeride Finasteride Saw palmetto extract
Others	* Abiraterone acetate +niraparib Aminoglutethimide Bifluranol Cyproterone acetate Flutamide Ketoconazole Nilutamide Seviteronel^† Spironolactone

Antigonadotropins

* D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)

Estrogens (e.g., bifluranol, diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
GnRH agonists (e.g., leuprorelin)
GnRH antagonists (e.g., cetrorelix)
Progestogens (incl., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)

Others

* Androstenedione immunogens: Androvax (androstenedione albumin)

Ovandrotone albumin (Fecundin)

Estrogens and antiestrogens

Estrogens

ER agonists

* Steroidal: Alfatradiol

Certain androgens/anabolic steroids (e.g., testosterone, testosterone esters, methyltestosterone, metandienone, nandrolone esters) (via estrogenic metabolites)
Certain progestins (e.g., norethisterone, noretynodrel, etynodiol diacetate, tibolone)
Clomestrone
Cloxestradiol acetate
Conjugated estriol
Conjugated estrogens
Epiestriol
Epimestrol
Esterified estrogens
Estetrol^†
Estradiol
Estradiol esters (e.g., estradiol acetate, estradiol benzoate, estradiol cypionate, estradiol enanthate, estradiol undecylate, estradiol valerate, polyestradiol phosphate, estradiol ester mixtures (Climacteron))
Estramustine phosphate
Estriol
Estriol esters (e.g., estriol succinate, polyestriol phosphate)
Estrogenic substances
Estrone
Estrone esters
- Estrone sulfate
- Estropipate (piperazine estrone sulfate)
Ethinylestradiol^#
- Ethinylestradiol sulfonate
Hydroxyestrone diacetate
Mestranol
Methylestradiol
Moxestrol
Nilestriol
Prasterone (dehydroepiandrosterone; DHEA)
- Prasterone enanthate
- Prasterone sulfate
Promestriene
Quinestradol
Quinestrol

Progonadotropins

* Antiandrogens (e.g., bicalutamide)

GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin)
Gonadotropins (e.g., FSH

, LH

)

Antiestrogens

ER antagonists (incl. SERMs /SERDs )	* Acolbifene^† Anordrin Bazedoxifene Broparestrol Clomifene^# Cyclofenil Enclomifene^† Epitiostanol Lasofoxifene Mepitiostane Ormeloxifene Ospemifene Raloxifene Tamoxifen^# Toremifene Exclusively antagonistic: Elacestrant Fulvestrant Noncompetitive inhibitors: Trilostane
Aromatase inhibitors	* First-generation: Aminoglutethimide Testolactone Second-generation: Fadrozole Formestane Third-generation: Anastrozole Exemestane Letrozole
Antigonadotropins	* Androgens/anabolic steroids (e.g., testosterone, testosterone esters, nandrolone esters, oxandrolone, fluoxymesterone) D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride) GnRH agonists (e.g., leuprorelin, goserelin) GnRH antagonists (e.g., cetrorelix, elagolix) Progestogens (e.g., chlormadinone acetate, cyproterone acetate, gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate)
Others	* Mixed mechanism of action: Danazol Gestrinone Androstenedione immunogens: Androvax (androstenedione albumin) Ovandrotone albumin (Fecundin)

Progestogens and antiprogestogens

Progestogens
(and progestins)

PR agonists

* Progesterone derivatives: Progesterone

Quingestrone

Retroprogesterone derivatives: Dydrogesterone
Trengestone

17α-Hydroxyprogesterone (and closely related) derivatives: 17α-Hydroxylated: Acetomepregenol (mepregenol diacetate)
Algestone acetophenide (dihydroxyprogesterone acetophenide)
Anagestone acetate
Chlormadinone acetate
Chlormethenmadinone acetate
Cyproterone acetate
Delmadinone acetate
Flugestone acetate (flurogestone acetate)
Flumedroxone acetate
Hydroxyprogesterone acetate
Hydroxyprogesterone caproate
Hydroxyprogesterone heptanoate
Medroxyprogesterone acetate^#
Megestrol acetate
Melengestrol acetate
Methenmadinone acetate
Osaterone acetate
Pentagestrone acetate
Proligestone; 17α-Methylated: Medrogestone; Others: Haloprogesterone

19-Norprogesterone derivatives: 17α-Hydroxylated: Gestonorone caproate (gestronol hexanoate)
Nomegestrol acetate
Norgestomet
Segesterone acetate (nestorone, elcometrine); 17α-Methylated: Demegestone
Promegestone
Trimegestone

Testosterone derivatives: Estranes: Danazol
Dimethisterone
Ethisterone

19-Nortestosterone derivatives: Estranes: Allylestrenol
Altrenogest
Dienogest
Etynodiol diacetate
Lynestrenol
Norethisterone (norethindrone)^#
Norethisterone acetate
Norethisterone enanthate
Noretynodrel
Norgesterone
Norgestrienone
Normethandrone (methylestrenolone)
Norvinisterone
Oxendolone
Quingestanol acetate
Tibolone; Gonanes: Desogestrel
Etonogestrel
Gestodene
Gestrinone
Levonorgestrel^#
Norelgestromin
Norgestimate
Norgestrel

Spirolactone derivatives: Drospirenone

Others: Anabolic–androgenic steroids (e.g., nandrolone and esters, trenbolone and esters, ethylestrenol, norethandrolone, others)

Antiprogestogens

SPRMs	* Telapristone^§ Ulipristal acetate
PR antagonists	* Aglepristone Mifepristone

GnRH and gonadotropins

GnRH modulators
(incl. analogues)

Agonists	* Peptide: Azagly-nafarelin Buserelin Deslorelin Fertirelin Gonadorelin Goserelin Histrelin Lecirelin Leuprorelin (leuprolide) Nafarelin Peforelin Triptorelin
Antagonists	* Peptide: Abarelix Cetrorelix Degarelix Ganirelix Non-peptide: Elagolix Linzagolix^† Relugolix^†

Gonadotropins

Preparations

* Follicle-stimulating hormone

Others
(indirect)

Progonadotropins

* Sex steroid antagonists (via disinhibition of the HPG axis): Antiandrogens (e.g., flutamide, bicalutamide, enzalutamide)

Antiestrogens/SERMs

(e.g., tamoxifen, clomifene, enclomifene)

Aromatase inhibitors (e.g., anastrozole)
GnRH agonists (e.g., GnRH

)

Antigonadotropins

* Sex steroid agonists (via negative feedback on the HPG axis): Androgens/anabolic steroids (e.g., testosterone, nandrolone esters, oxandrolone)

D₂ receptor antagonists (prolactin releasers) (incl., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
Estrogens (incl., bifluranol, estradiol, estradiol esters, ethinylestradiol, diethylstilbestrol, paroxypropione)
Progestogens (incl. progestins, e.g., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)

Others (mixed or unknown mechanism of action): Danazol
Gestrinone
Metallibure

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Latest revision as of 03:08, 17 March 2025

L02A Hormones and related agents[edit]

L02AA Estrogens[edit]

L02AB Progestogens[edit]

L02AE Gonadotropin-releasing hormone analogues[edit]

L02AX Other hormones[edit]

L02B Hormone antagonists and related agents[edit]

L02BA Anti-estrogens[edit]

L02BB Anti-androgens[edit]

L02BG Aromatase inhibitors[edit]

L02BX Other hormone antagonists and related agents[edit]

References[edit]