Lasofoxifene
Lasofoxifene
Lasofoxifene (pronunciation: la-so-fox-i-fene) is a Selective Estrogen Receptor Modulator (SERM) that is primarily used in the treatment of osteoporosis in postmenopausal women. It is also being studied for its potential use in the treatment of breast cancer and vaginal atrophy.
Etymology
The term 'Lasofoxifene' is derived from the chemical name of the drug, which is laso (from Latin lasus meaning 'loose') and foxifene (from Latin foxus meaning 'fox' and fene meaning 'fen', a type of wetland). The name suggests the drug's ability to selectively bind to estrogen receptors, much like a fox navigating through a fen.
Usage
Lasofoxifene is used to treat and prevent osteoporosis in postmenopausal women. It works by mimicking the effects of estrogen, a hormone that helps to maintain bone density. By binding to estrogen receptors in the bone, lasofoxifene helps to slow the rate of bone loss and reduce the risk of fractures.
Related Terms
- Selective Estrogen Receptor Modulator (SERM): A type of drug that acts on the estrogen receptors in the body. SERMs can either mimic the effects of estrogen (agonist action) or block its effects (antagonist action), depending on the tissue.
- Osteoporosis: A condition characterized by a decrease in bone density, which can lead to an increased risk of fracture.
- Breast Cancer: A type of cancer that forms in the cells of the breasts. Some forms of breast cancer are sensitive to hormones, including estrogen.
- Vaginal Atrophy: A condition in postmenopausal women characterized by a thinning, drying and inflammation of the vaginal walls due to a decrease in estrogen.
External links
- Medical encyclopedia article on Lasofoxifene
- Wikipedia's article - Lasofoxifene
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