Toremifene

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Toremifene

Toremifene (pronounced: toh-REM-ih-feen) is a medication used in the treatment of advanced breast cancer in postmenopausal women. It is a nonsteroidal anti-estrogen drug, specifically a selective estrogen receptor modulator (SERM), and works by blocking the effects of estrogen in the breast tissue.

Etymology

The name "Toremifene" is derived from its chemical name, which is 2-{p-[(Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy}-N,N-dimethylethylamine. The "Tore" part of the name is an abbreviation of the chemical structure, while "mifene" is a common suffix for drugs in the SERM class.

Usage

Toremifene is used primarily in the treatment of metastatic breast cancer in postmenopausal women. It is also being studied for use in the prevention of prostate cancer in men. Toremifene works by binding to estrogen receptors in cancer cells, blocking the effects of estrogen and slowing the growth of the cancer.

Side Effects

Common side effects of Toremifene include hot flashes, sweating, nausea, and vaginal discharge. More serious side effects can include blood clots, stroke, and endometrial cancer. Patients should discuss these risks with their doctor before starting treatment.

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