Estriol succinate

Estriol succinate is a synthetic estrogen that is used in hormone replacement therapy. It is a salt of estriol, a naturally occurring estrogen, and succinic acid, a dicarboxylic acid. The compound is used to treat symptoms of menopause, such as hot flashes and vaginal dryness.

Etymology

The term "estriol" is derived from the Greek word "oistros", meaning "gadfly" or "frenzy", and the suffix "-ol", which is used in chemistry to denote an alcohol. The term "succinate" comes from the Latin "succus", meaning "juice", and the suffix "-ate", which is used in chemistry to denote a salt or ester of an acid.

Pharmacology

Estriol succinate acts by binding to estrogen receptors in the body, mimicking the effects of natural estrogens. This can help to alleviate symptoms of menopause, which are caused by a decrease in the body's natural estrogen levels.

Side Effects

Like all medications, estriol succinate can cause side effects. These may include nausea, vomiting, bloating, breast tenderness, and headache. More serious side effects can include blood clots, stroke, and cancer of the uterus or breast.

Related Terms

• Estrogen: A group of hormones that play an important role in the normal sexual and reproductive development in women.
• Hormone replacement therapy: A treatment for symptoms of menopause that involves taking supplemental hormones.
• Menopause: The time in a woman's life when menstrual periods permanently stop, also called the "change of life."

See Also

• Estradiol
• Estrone
• Progesterone

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