Benzestrol

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Benzestrol

Benzestrol (pronounced ben-ZES-trol) is a synthetic, nonsteroidal estrogen that was formerly used in medicine for a variety of indications, including menopausal symptoms and prostate cancer, but is now rarely used due to its association with health risks.

Etymology

The term "Benzestrol" is derived from the chemical structure of the compound, which includes a benzene ring and an estrogenic phenol group. The "-estrol" suffix is common in the names of synthetic estrogens.

Usage

Benzestrol was primarily used as a form of hormone therapy for menopausal symptoms such as hot flashes and vaginal dryness. It was also used in the treatment of prostate cancer due to its ability to suppress testosterone production. However, its use has declined significantly due to the discovery of safer and more effective treatments.

Side Effects

Like other estrogens, Benzestrol can cause a number of side effects, including nausea, bloating, breast tenderness, and an increased risk of blood clots and stroke. Long-term use has been associated with an increased risk of endometrial cancer.

Related Terms

  • Estrogen: A group of hormones that play an important role in the normal sexual and reproductive development in women.
  • Hormone therapy: Treatment of disease or symptoms with synthetic hormones.
  • Prostate cancer: A form of cancer that develops in the prostate, a gland in the male reproductive system.
  • Endometrial cancer: A type of cancer that begins in the lining of the uterus (endometrium).

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