Nafarelin

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Nafarelin (pronounced na-fa-REL-in) is a type of gonadotropin-releasing hormone (GnRH) agonist. It is a synthetic form of GnRH used primarily in the treatment of endometriosis and central precocious puberty.

Etymology

The term "Nafarelin" is derived from the chemical name Nafarelin acetate, which is a decapeptide. It is a modified form of the naturally occurring gonadotropin-releasing hormone (GnRH).

Usage

Nafarelin is used to manage endometriosis, a condition where the tissue that normally lines the uterus grows in other parts of the body. It is also used to treat central precocious puberty, a condition causing children to enter puberty too soon.

Mechanism of Action

Nafarelin works by decreasing the amount of certain hormones in the body including estrogen in women and testosterone in men. This effect helps to reduce symptoms such as pain in endometriosis and slows down early puberty in children.

Related Terms

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