Estradiol undecylate

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Estradiol Undecylate

Estradiol undecylate (pronunciation: es-tra-DYE-ole un-DE-si-late) is a synthetic, steroidal estrogen that is used in hormone therapy. It is a long-acting ester of estradiol, the primary female sex hormone.

Etymology

The term "estradiol" is derived from estrus (Latin for "gadfly" or "frenzy"), -o- (a common infix in organic chemistry), and -diol (a chemical term denoting a certain type of alcohol). "Undecylate" refers to the undecylic acid ester that is formed with estradiol in this compound.

Usage

Estradiol undecylate is used primarily in hormone replacement therapy for menopausal symptoms. It is also used in the treatment of low estrogen levels, prostate cancer, and in feminizing hormone therapy for transgender women.

Pharmacology

Estradiol undecylate is a prodrug of estradiol, meaning it is metabolized in the body into estradiol. It is administered via intramuscular injection and has a very long duration of action due to its long-chain fatty acid ester.

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