Chlormethenmadinone acetate

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Chlormethenmadinone acetate

Chlormethenmadinone acetate (pronunciation: klor-meth-en-mad-i-none as-et-ate) is a progestin medication which is used in hormone therapy. It is an acetate ester of chlormadinone, a synthetic, steroidal progestin with antiandrogenic activity.

Etymology

The term "Chlormethenmadinone acetate" is derived from its chemical structure. "Chlor" refers to the presence of a chlorine atom, "methen" refers to the methylene group, "madinone" is a suffix used in the nomenclature of steroidal compounds, and "acetate" refers to the presence of an acetate group.

Usage

Chlormethenmadinone acetate is used in the treatment of menopausal symptoms, gynecological disorders, and in combination with estrogen as a component of hormone replacement therapy. It is also used in the treatment of prostate cancer due to its antiandrogenic properties.

Pharmacology

Chlormethenmadinone acetate works by binding to and activating the progesterone receptor, thereby inhibiting the release of gonadotropins and preventing ovulation. Its antiandrogenic activity is due to its ability to compete with testosterone and dihydrotestosterone for binding to the androgen receptor.

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