Nafoxidine
Nafoxidine
Nafoxidine (pronounced: na-fox-i-dine) is a nonsteroidal estrogen antagonist that was initially developed for the treatment of breast cancer. It is also known as U-11,000A.
Etymology
The term "Nafoxidine" is derived from the chemical name N-[[4-(2-p-(acetyloxy)phenyl-2-phenylmethyl-1-piperazinyl)phenyl]]-2-naphthalenyloxyacetamide.
Usage
Nafoxidine was initially developed as a potential treatment for breast cancer due to its ability to block the effects of estrogen in the body. However, it was never approved for this use due to concerns about its safety and efficacy. Despite this, Nafoxidine has been used in research settings to study the effects of estrogen antagonists on various biological processes.
Related Terms
- Estrogen: A group of hormones that play an important role in the normal sexual and reproductive development in women.
- Breast Cancer: A type of cancer that forms in the cells of the breasts.
- Estrogen Antagonist: A substance that blocks the effects of estrogen in the body.
- Nonsteroidal: A term used to describe drugs that are not based on the steroid molecule.
See Also
- Tamoxifen: Another nonsteroidal estrogen antagonist that is commonly used in the treatment of breast cancer.
- Fulvestrant: A selective estrogen receptor degrader (SERD) that is used in the treatment of hormone receptor-positive metastatic breast cancer.
External links
- Medical encyclopedia article on Nafoxidine
- Wikipedia's article - Nafoxidine
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