Afimoxifene

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Afimoxifene (pronounced as a-fi-mox-i-fen) is a Selective Estrogen Receptor Modulator (SERM) that is used in the treatment of Breast Cancer. It is a derivative of Tamoxifen, and is also known by its brand name, 4-Hydroxytamoxifen.

Etymology

The term "Afimoxifene" is derived from its chemical structure. The prefix "Afi-" is derived from the chemical name 4-Hydroxytamoxifen, and "-moxifene" is a common suffix used in the names of SERMs.

Pharmacology

Afimoxifene binds to Estrogen Receptors in the body, blocking the effects of estrogen. This can help to slow the growth of certain types of breast cancer cells that require estrogen to grow.

Usage

Afimoxifene is used in the treatment of hormone receptor-positive breast cancer. It is typically used in postmenopausal women, but can also be used in premenopausal women in combination with other treatments.

Side Effects

Common side effects of Afimoxifene include hot flashes, nausea, and fatigue. More serious side effects can include blood clots, stroke, and endometrial cancer.

Related Terms

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